出版:
2022年2月22日
通过与主要合作伙伴和供应商的合作，在“零碳雄心”方面取得进展
澳门葡京赌博游戏与霍尼韦尔合作开发下一代吸入器，其推进剂的全球变暖潜值(GWP)接近零，这表明澳门葡京赌博游戏致力于改善患者的治疗效果，保护患者的选择, while reducing our environmental footprint.
Since we launched our flagship sustainability programme Ambition Zero Carbon, the devastation caused by COVID-19 has led to extraordinary changes across the world. Something that remains unchanged, 然而, 气候紧急情况是否有可能成为对人类健康的最大威胁之一.1 Together with partners across our value chain, 澳门葡京赌博游戏正在采取具体步骤，减少护理对环境的影响，以支持健康人群, healthy society and a healthy planet.
在这段简短的视频中，听澳门葡京赌博游戏的高级管理团队成员讨论澳门葡京赌博游戏实现零碳雄心的过程:
推进澳门葡京赌博游戏的下一代加压计量吸入器(pmdi)与接近零的全球变暖潜能值(GWP)推进剂
We’re partnering with Honeywell to develop a next-generation pMDI, using the propellant HFO-1234ze which has up to 99.9% less GWP than propellants currently used in respiratory medicines.2 This is an innovation that is extremely important given the clinical need for pMDIs.3-7
Globally, as many as 339 million children and adults are affected by asthma8 and up to 384 million people live with chronic obstructive pulmonary disease (COPD).9 For many of these people, pMDIs are an important therapeutic option,3-7 as these inhaled medicines reduce COPD exacerbations and asthma attacks, which are potentially life-threatening events.10-11 然而, pmdi含有少量的温室气体(GHG)，促使药物进入肺部.12
重要的是要认识到，呼吸疾病控制不佳可能会大大增加呼吸护理的碳足迹.13 因此, 优先考虑最佳疾病管理不仅可以改善患者的预后，还可以对环境产生积极影响. 例如, 数据显示，与控制良好的哮喘相比，不受控制的哮喘与碳足迹增加有关.13 过量的温室气体排放来自常规的全科医生就诊和哮喘发作导致的医院护理，以及过度依赖短效β 2激动剂吸入器(每年吸入3次或更多)。.13
Chronic respiratory diseases can seriously affect patients’ lives, and it is crucial to tailor treatment to individual patient need. 澳门葡京赌博游戏知道，全球有数百万患者使用pmdi来帮助预防哮喘发作和慢性阻塞性肺病恶化. 很高兴看到接近零全球变暖潜力的推进剂正在开发中，这将确保患者继续选择, 并提供可行的解决方案，以减少加压计量吸入器对环境的影响.
On track to deliver Ambition Zero Carbon commitments
澳门葡京赌博游戏与霍尼韦尔的合作是澳门葡京赌博游戏在可持续发展承诺方面取得进展的一个例子. With science as our guiding principle, 澳门葡京赌博游戏的目标是到2025年底在全球业务中实现零碳排放，到2030年在整个价值链中实现负碳排放. 在澳门葡京网赌游戏，澳门葡京赌博游戏所有的进口电力现在都来自可再生能源，到2021年底, 与2015年的基准相比，澳门葡京赌博游戏的第一类和第二类温室气体排放量减少了59%, including the integration of Alexion AstraZeneca 罕见的疾病’s footprint.13 澳门葡京赌博游戏的 2021 可持续性 Report outlines our progress and commitments in further detail.
Taking net zero to the next step
澳门葡京赌博游戏认识到，与他人合作对于推动整个系统的变革至关重要. Like many other companies, 澳门葡京赌博游戏的大部分排放都在澳门葡京赌博游戏自己的运营之外，因此参与整个价值链对澳门葡京赌博游戏减少第3类排放至关重要. That is why we have set the goal that by the end of 2025, 95% of our key suppliers and partners will have science-based targets to limit global warming to <1.5C.13
As a global business pushing the boundaries of science to deliver life-changing medicines, 澳门葡京赌博游戏致力于与利益相关者合作，共同建设可持续发展的未来.
引用:
1. 谁. Climate change and health. (在线). Available at: http://www.谁.int/news-room/fact-sheets/detail/climate-change-and-health. [Last accessed: February 2022].
2. AstraZeneca Pharmaceuticals. 存档日期. Global Warming Potential of HFO-1234ze. (ID: ref - 140251)
3. Lavorini F. The challenge of delivering therapeutic aerosols to asthma patients. ISRN过敏. 2013;102418.
4. Usmani操作系统, 等. Inhaler choice guideline. Choosing an appropriate inhaler device for the treatment of adults with asthma or COPD. 2017. Available at: http://www.的指导方针.co.uk/respiratory/inhaler-choice-guideline/252870.article [Last accessed: February 2022]
5. 罗氏N, 等. The evolution of pressurized metered-dose inhalers from early to modern devices. J Aerosol Med Pulm Drug Deliv. 2016;4:311–27.
6. Laube提单, 等. What the pulmonary specialist should know about the new inhalation therapies. Eur呼吸器. 2011;37:1308-31.
7. Lavorini F, 等. 老年慢性阻塞性肺疾病患者吸入药物治疗优化:输送装置的重要性. 药物老化. 2016;33:461–73.
8. The Global Asthma Network. The Global Asthma Report 2018. (在线). Available at: http://www.globalasthmareport.org/Global%20Asthma%20Report%202018.pdf. [Last accessed: Februayr 2022].
9. Adeloye D, 等. Global Health Epidemiology Reference Group (GHERG). Global and regional estimates of COPD prevalence: Systematic review and meta-analysis. J Glob Health. 2015; 5 (2): 020415.
10. Beasley RW，等. Controlled trial of budesonide-formoterol as needed for mild asthma. [英]医学. 2019;380 (21):2020–2030.
11. Ferguson GT，等. 布地奈德/福莫特罗加压计量吸入器对慢性阻塞性肺疾病加重的影响:6个月, 随机RISE(揭示喜必可降低COPD加重的影响)研究. 和地中海. 2017; 132: 31‐41
12. ·迈尔德尔铅、 等. Advances in metered dose inhaler technology: formulation development. aap PharmSciTech. 2014;15(2):434–455.
13. AstraZeneca Pharmaceuticals. 澳门葡京网赌游戏与霍尼韦尔合作推进雄心零碳计划，开发下一代呼吸吸入器. (在线). Available at: http://fajknd8.dektinary.com/content/astraz/media-centre/press-releases/2022/澳门葡京网赌游戏-progresses-ambition-zero-carbon-programme-with-honeywell-partnership-to-develop-next-generation-respiratory-inhalers.html. [Last accessed: February 2022].